The Body's Defenses
Campbell Chapter 39

1. Outline the immune system's three lines of defense.

2. What role is played by the skin and mucous membranes?

3. What role is played by macrophages?

4. What is the job of the natural killer cell?

5. Describe the action of complement system.

6. Describe the inflammatory response. Identify the purpose served by each component of the response.

7. Explain the four components of the immune system.

8. Distinguish between active and passive immunity.

9. What is the key component of the humoral immune system?

10. What is the key component of the cell-mediated immune system?

11. What is an antigen?

12. What is an epitope?

13. Explain how the clonal selection of B cells occurs.

14. What important role is played by memory B cells?

15. Explain the response to a T-dependant antigen (remember, this requires macrophages and T_H cells).

16. How is a T cell activated by an APC and what is the result?

17. What are cytokines?

18. Describe the genetic basis for our ability to produce B cells with such a wide range of specificities.

19. Describe the mechanisms by which antibodies function.

20. What is a cytotoxic T cell? How does it work?

21. What is perforin?

22. What are monoclonal antibodies and how can they be used?

23. Describe the antigen/antibody reactions possible in blood transfusions.

24. Why is the immune system an issue in organ transplantation?

25. Describe the allergic response.

26. Explain the transmission, effects, and treatment of HIV and AIDS.