Membrane Structure and Function
Campbell Chapter 8

1. Make a simple drawing of the fluid mosaic model of the cell membrane. Be sure to include phospholipids, integral and peripheral proteins, glycoproteins, glycolipids, cholesterol, and some components of the ECM.

2. Describe the fluid mosaic model of the cell membrane and explain its significance to the cell. How is membrane fluidity maintained? Be sure to mention phospholipid molecules, hydrophobic and hydrophilic ends, types of membrane proteins and glycoproteins. Indicate substances to which the membrane is relatively permeable and those substances to which it is relatively impermeable.

3. What is the role of the rough ER and Golgi in the formation of membranes?

4. Describe the functions of membrane proteins, including signal transduction.

5. What factors contribute to the selective permeability of the cell membrane?

6. Define both diffusion and osmosis and explain what causes each.

7. How does the random movement of molecules bring about an even distribution of molecules throughout the system?

8. Define the terms hypotonic, hypertonic and isotonic and explain what would happen to a cell if it were placed in each of these solutions.

9. Explain why a concentration gradient across a membrane represents potential energy.

10. How do living cells with and without walls regulate water balance?

11. What is facilitated diffusion?

12. Explain how active transport differs from diffusion.

13. Distinguish between simple diffusion, facilitated diffusion, and active transport and indicate the significance of these processes to the life of the cell.

14. Explain how the sodium-potassium pump generates a membrane potential or electrochemical gradient.

15. Describe cotransport and explain how it is useful to cells?

16. Define the following terms: exocytosis, endocytosis, phagocytosis, pinocytosis, receptor-mediated endocytosis, turgor pressure.