The Molecular Basis of Inheritance

Chapter 16

1. Describe the model of DNA proposed by Watson and Crick. Include a description of what the monomers are and how they are connected together.

2. Why do the purine and pyrimidine bases always pair together?

3. Outline the process of DNA replication. Be sure to include all of the relevant enzymes.

4. Building DNA is an endergonic process. What is the source of energy?

5. DNA replication proceeds along both strands in both directions from the origin. How is the problem of the antiparallel strands solved?

6. Why is primase required in DNA replication?

7. How are the spaces between fragments filled?

8. Explain how errors are corrected during and after DNA replication. Explain the importance of DNA proofreading and repair.

9. What makes complimentary base pairing so useful for DNA replication and detecting errors?

10. What is the problem associated with replicating the ends of chromosomes? How is the problem solved?