Eukaryotic Genomes: Organization, Regulation, and Evolution

Chapter 19


1. Briefly describe the levels of DNA packing in eukaryotic cells.

2. What role do histones play in DNA packing?

3. Be sure you could describe the stages in gene expression that can be regulated by eukaryotic cells.

4. How does histone acetylation affect gene expression? DNA methylation?

5. Explain the roles of enhancers and transcription factors in regulating gene expression.

6. How can a group of genes be turned on simultaneously?

7. Explain the role of RNAi in regulating gene expression.

8. How can the life of a mRNA be extended? Why would a cell do this?

9. Explain the role of oncogenes and tumor-suppressor genes in the development of cancer.\

10. What are the three types of DNA found in the human genome?

11. Explain how a transposon can move within the genome.

12. How could multigene families have arisen? How would this be useful to a cell?